active ingredient of silymarin
extract derived from herb milk thistle a member of compositae or daisy family
containing mixture of flavonolignans consisting of among others of silibinin, isosilibinin, silicristin and silidianin
The most abundant and potent costituents in silymarin are two diastereoisomeric compounds (silybin A and silybin B) known as silybin (also called silibinin)
Silymarin has been shown to be effective in the treatment of liver diseases of various kinds, including hepatitis, cirrhosis, fatty infiltration of the liver (alcoholic- and non-alcoholic fatty liver), and inflammation of the bile ducts
prevent toxic liver damage
speed up liver regeneration
A recent studies in vitro by Zi and Agarwal (1999) found that silibinin was able to arrest cell growth in prostate cancer lines, probably by inhibiting various kinase enzymes. Silibinin helped arrest cell growth in the early phase of the cell cycle, known as G1. The researchers found a 20% increase in G1 cell population when the culture was treated with silibinin.they fount interestingly that the growth arrrest occured by cell differentiation.
its efffect on heart
in studies conducted by Schriewer and Rauen 1977they found that it inhibits the biosynthesis of cholesterol invitro they also abserved elimination of lipoproteins in presence of it.Studies have also shown that silymarin and silibinin inhibit the development of diet-related excess cholesterol levels in rats. Supplementing the diet with silymarin or silibinin resulted in an increase in HDL levels and a decrease in liver cholesterol content.
antioxident
Silibinin has been found to protect red blood vessels and stabilize their membranes through inhibition of lipid peroxidation. In addition, silibinin increases the activity of the antioxidant enzymes superoxide dismutase (SOD) and glutathione peroxidase in human red blood cells (Altorjay 1992)
3959BA97962059284AD378689ABB7B22
extract derived from herb milk thistle a member of compositae or daisy family
containing mixture of flavonolignans consisting of among others of silibinin, isosilibinin, silicristin and silidianin
The most abundant and potent costituents in silymarin are two diastereoisomeric compounds (silybin A and silybin B) known as silybin (also called silibinin)
Silymarin has been shown to be effective in the treatment of liver diseases of various kinds, including hepatitis, cirrhosis, fatty infiltration of the liver (alcoholic- and non-alcoholic fatty liver), and inflammation of the bile ducts
prevent toxic liver damage
speed up liver regeneration
A recent studies in vitro by Zi and Agarwal (1999) found that silibinin was able to arrest cell growth in prostate cancer lines, probably by inhibiting various kinase enzymes. Silibinin helped arrest cell growth in the early phase of the cell cycle, known as G1. The researchers found a 20% increase in G1 cell population when the culture was treated with silibinin.they fount interestingly that the growth arrrest occured by cell differentiation.
its efffect on heart
in studies conducted by Schriewer and Rauen 1977they found that it inhibits the biosynthesis of cholesterol invitro they also abserved elimination of lipoproteins in presence of it.Studies have also shown that silymarin and silibinin inhibit the development of diet-related excess cholesterol levels in rats. Supplementing the diet with silymarin or silibinin resulted in an increase in HDL levels and a decrease in liver cholesterol content.
antioxident
Silibinin has been found to protect red blood vessels and stabilize their membranes through inhibition of lipid peroxidation. In addition, silibinin increases the activity of the antioxidant enzymes superoxide dismutase (SOD) and glutathione peroxidase in human red blood cells (Altorjay 1992)
3959BA97962059284AD378689ABB7B22






